CD45R Antibody [RA3-6B2]
Product Specifications
Background
CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.
NCBI Gene ID
19264
Swiss Prot
P06800
Accession Number
P06800
Host
Rat
Reactivity
Mouse, Human, Cat
Immunogen
Abelson murine leukemia virus-induced pre-B cell lymphoma
Clonality
Monoclonal
Clone
[RA3-6B2]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=98-785
Fragment
IgG2a
Specificity
CD45R
Applications Notes
CD45R Antibody [RA3-6B2] for use in flow cytometry, immunohistochemistry, western blotting, immunoprecipitation, and blocking assays.
Symbol
Ptprc
NCBI Official Name
Protein tyrosine phosphatase, receptor type, C
NCBI Organism
Mus musculus
Other Product Names
B220, Ly-5, Lyt-4, Ptprc, Receptor-type tyrosine-protein phosphatase C
Tested Applications
Flow
Physical Properties
Liquid
Curated Selection
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