CD28 Antibody [PV-1]
Product Specifications
Background
CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a costimulatory receptor involved in many, but not all, T-cell independent immune responses.
NCBI Gene ID
12487
Swiss Prot
P31041
Accession Number
P31041
Host
Hamster
Reactivity
Mouse
Immunogen
C57BL/6N mouse T cell lymphoma EL4 cell line
Clonality
Monoclonal
Clone
[PV-1]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG
Specificity
CD28
Applications Notes
CD28 Antibody [PV-1] for use in flow cytometry, immunoprecipitation, costimulation, and stimulation assays.
Symbol
Cd28
NCBI Official Name
CD28 antigen
NCBI Organism
Mus musculus
Other Product Names
Tp44, T44
Tested Applications
IHC-P, IHC-Fr, ICC, Flow
Physical Properties
Liquid
Frequently Asked Questions
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