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CD28 Antibody [37.51]

Product Specifications

Background

CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a costimulatory receptor involved in many, but not all, T-cell independent immune responses.

NCBI Gene ID

12487

Swiss Prot

P31041

Accession Number

P31041

Host

Hamster

Reactivity

Mouse

Immunogen

C57BL/6N mouse T cell lymphoma EL-4 cell line

Clonality

Monoclonal

Clone

[37.51]

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Concentration

0.5 mg/mL

Buffer

Supplied in PBS

Modification

None

Shipping Conditions

Dry Ice

Storage Conditions

Store vial at -20˚ C

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=98-719

Fragment

IgG

Specificity

CD28

Applications Notes

CD28 Antibody [37.51] for use in flow cytometry, immunoprecipitation, costimulation, stimulation, activation, and blocking assays.

Symbol

Cd28

NCBI Official Name

CD28 antigen

NCBI Organism

Mus musculus

Other Product Names

Tp44, T44

Tested Applications

ELISA, IHC-P, IHC-Fr, ICC, Flow, IP

Physical Properties

Liquid

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