CD28 Antibody [37.51]
Product Specifications
Background
CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a costimulatory receptor involved in many, but not all, T-cell independent immune responses.
NCBI Gene ID
12487
Swiss Prot
P31041
Accession Number
P31041
Host
Hamster
Reactivity
Mouse
Immunogen
C57BL/6N mouse T cell lymphoma EL-4 cell line
Clonality
Monoclonal
Clone
[37.51]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG
Specificity
CD28
Applications Notes
CD28 Antibody [37.51] for use in flow cytometry, immunoprecipitation, costimulation, stimulation, activation, and blocking assays.
Symbol
Cd28
NCBI Official Name
CD28 antigen
NCBI Organism
Mus musculus
Other Product Names
Tp44, T44
Tested Applications
IHC-P, Flow
Physical Properties
Liquid
Frequently Asked Questions
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