CD19 Antibody [MB19-1] (PE)
Product Specifications
Background
CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.
NCBI Gene ID
12478
Swiss Prot
P25918
Accession Number
P25918
Host
Mouse
Reactivity
Mouse
Immunogen
CD19+ mouse pre-B cell line 300.19
Clonality
Monoclonal
Clone
[MB19-1]
Conjugation
PE
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.1 mg/mL
Buffer
Supplied in PBS/NaN3 and a stabilizing agent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=98-670
Fragment
IgA
Specificity
CD19
Applications Notes
CD19 Antibody [MB19-1] for use in flow cytometry assays.
Symbol
Cd19
NCBI Official Name
CD19 antigen
NCBI Organism
Mus musculus
Other Product Names
B4, Leu-12
Tested Applications
WB, IHC-P, ICC, Flow
Physical Properties
Liquid
Curated Selection
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