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CD18 Antibody [C71/16]

Product Specifications

Background

CD18 represents the common beta2 integrin subunit that associates non-covalently with the alpha/beta chains of CD11a, CD11b, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes and weakly on granulocytes. CD18 mediates a variety of heterotypic and homotypic intercellular adhesion reactions and it regulates the ligand-binding activates of the various CD11/CD18 complexes. The monoclonal antibody C71/16 has not been reported to inhibit cell adhesion.

NCBI Gene ID

16414

Swiss Prot

P11835

Accession Number

P11835

Host

Rat

Reactivity

Mouse

Immunogen

Cell membrane glycoproteins derived from mouse BW5147 T cell lymphoma cells

Clonality

Monoclonal

Clone

[C71/16]

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Concentration

0.5 mg/mL

Buffer

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store vial at 2-8˚ C

Fragment

IgG2a

Specificity

CD18

Applications Notes

CD18 Antibody [C71/16] for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blotting, and immunoprecipitation assays.

Symbol

Itgb2

NCBI Official Name

Integrin beta 2

NCBI Organism

Mus musculus

Other Product Names

Integrin beta2, ITGB2

Tested Applications

ELISA, IHC-Fr, ICC, Flow, IP

Physical Properties

Liquid

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