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CD11a Antibody [I21/7] (PE-Cy7)

Product Specifications

Background

The monoclonal antibody I21/7 reacts with the alpha subunit of mouse and human CD11a, also known as LFA-1, and a member of the integrin family of cell adhesion molecules. The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Costimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1.

NCBI Gene ID

16408

Swiss Prot

P24063

Accession Number

P24063

Host

Rat

Reactivity

Mouse, Human

Immunogen

Whole BW5147 cells

Clonality

Monoclonal

Clone

[I21/7]

Conjugation

PE-Cy7

Type

Primary Antibodies

Field of Research

Cancer

Concentration

0.1 mg/mL

Buffer

Supplied in PBS/NaN3 and a stabilizing agent

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store vial at 2-8˚ C

Fragment

IgG2a

Specificity

CD11a

Applications Notes

CD11a Antibody [I21/7] for use in flow cytometry assays.

Symbol

Itgal

NCBI Official Name

Integrin alpha L

NCBI Organism

Mus musculus

Other Product Names

LFA-1, LFA-1alpha, integrin alphaL

Tested Applications

ELISA, IHC-Fr, ICC, Flow, Neutralization Assay

Physical Properties

Liquid

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