CD11a Antibody [I21/7]
Product Specifications
Background
The monoclonal antibody I21/7 reacts with the alpha subunit of mouse and human CD11a, also known as LFA-1, and a member of the integrin family of cell adhesion molecules. The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Costimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1.
NCBI Gene ID
16408
Swiss Prot
P24063
Accession Number
P24063
Host
Rat
Reactivity
Mouse, Human
Immunogen
Whole BW5147 cells
Clonality
Monoclonal
Clone
[I21/7]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2a
Specificity
CD11a
Applications Notes
CD11a Antibody [I21/7] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.
Symbol
Itgal
NCBI Official Name
Integrin alpha L
NCBI Organism
Mus musculus
Other Product Names
LFA-1, LFA-1alpha, integrin alphaL
Tested Applications
ELISA, IHC-Fr, ICC
Physical Properties
Liquid
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