CD44 Antibody [KM201]
Product Specifications
Background
CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.
NCBI Gene ID
12505
Swiss Prot
P15379
Accession Number
P15379
Host
Rat
Reactivity
Mouse
Immunogen
(C57BL/6 x DBA/2) F1 mouse bone marrow-derived stromal clone BMS2
Clonality
Monoclonal
Clone
[KM201]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Concentration
0.5 mg/mL
Buffer
Supplied in PBS
Modification
None
Shipping Conditions
Dry Ice
Storage Conditions
Store vial at -20˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=98-543
Fragment
IgG1
Specificity
CD44
Applications Notes
CD44 Antibody [KM201] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, blocking, and adhesion assays.
Symbol
Cd44
NCBI Official Name
CD44 antigen
NCBI Organism
Mus musculus
Other Product Names
Pgp-1, H-CAM, HUTCH-1, ECMR-III
Tested Applications
ELISA, WB, IHC-P, IHC-Fr, ICC
Physical Properties
Liquid
Curated Selection
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