Fibrillin Antibody [11C1.3]
Product Specifications
Background
The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear. There is an aberrant expression of fibrillin in Marfan syndrome. The epitope for the monoclonal antibody 11C1.3 has been found to be within exons 18-20 (a.a. 723-909) .
NCBI Gene ID
2200
Swiss Prot
Q75N89
Accession Number
Q75N89
Host
Mouse
Reactivity
Human, Bovine, Japanese Macaque
Immunogen
Microfibrils from the zonular apparatus of bovine eye
Clonality
Monoclonal
Clone
[11C1.3]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Concentration
0.2 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=98-519
Fragment
IgG1
Specificity
Fibrillin
Applications Notes
Fibrillin Antibody [11C1.3] for use in immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, and immunoprecipitation assays.
Symbol
FBN1
NCBI Official Name
Fibrillin 1
NCBI Organism
Homo sapiens
Other Product Names
FBN1
Tested Applications
Flow
Physical Properties
Liquid
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