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VEGFR1 (phospho Tyr1213) Antibody

Product Specifications

Background

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

NCBI Gene ID

2321

Swiss Prot

P17948

Accession Number

NP_001153392.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

VEGFR1 (phospho Tyr1213) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 1213 (V-R-Y (p) -V-N) derived from Human VEGFR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

90 kDa

Fragment

IgG

Specificity

The antibody detects endogenous level of VEGFR1 only when phosphorylated at tyrosine 1213.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

FLT1

NCBI Official Name

Fms-related tyrosine kinase 1

NCBI Organism

Homo sapiens

Background Reference 01

Raghu H, et al. (2012) Mol Oncol 6, 33-47

Background Reference 02

Ito N, Huang K, Claesson-Welsh L (2001) Cell Signal 13, 849-54

Background Reference 03

Ito N, Wernstedt C, Engström U, Claesson-Welsh L (1998) J Biol Chem 273, 23410-8

Other Product Names

FLT, FLT1, FRT, Flt-1, Fms-like tyrosine kinase 1

Tested Applications

WB

Protein ID

143811474

Physical Properties

Liquid

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