Calmodulin (phospho Thr79/Ser81) Antibody

Product Specifications

Background

Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.

NCBI Gene ID

808

Swiss Prot

P62158

Accession Number

NP_005175.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Calmodulin (phospho Thr79/Ser81) antibody was raised against a peptide sequence around phosphorylation site of threonine79/serine81 (K-D-T (p) -D-S (p) -E-E) derived from Human Calmodulin .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

17 kDa

Fragment

IgG

Specificity

The antibody detects endogenous level of Calmodulin only when phosphorylated at threonine 79/serine 81.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

CALM3

NCBI Official Name

Calmodulin 3 (phosphorylase kinase, delta)

NCBI Organism

Homo sapiens

Background Reference 01

Allen D, Fakler B, Maylie J, Adelman JP (2007) J Neurosci 27, 2369-76

Background Reference 02

Arrigoni G, et al. (2004) Biochemistry 43, 12788-98

Background Reference 03

Greif DM, Sacks DB, Michel T (2004) Proc Natl Acad Sci U S A 101, 1165-70

Other Product Names

CALM, CALM1, CALM2, CALM3, CAM

Tested Applications

Protein ID

58218968

Physical Properties

Liquid

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