STAT5A/B (phospho Ser725/730) Antibody
Product Specifications
Background
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
NCBI Gene ID
6776;6777
Swiss Prot
P42229; P51692
Accession Number
NP_001275647.1; NP_036580.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
90 kDa
Fragment
IgG
Specificity
The antibody detects endogenous level of STAT5A/B only when phosphorylated at serine 725/ serine 730.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
STAT5A, STAT5B
NCBI Official Name
Signal transducer and activator of transcription 5A, signal transducer and activator of transcription 5B
NCBI Organism
Homo sapiens
Background Reference 01
Ross JA, et al. (2010) J Biol Chem 285, 3582-91
Background Reference 02
Uddin S, et al. (2003) Biochem Biophys Res Commun 308, 325-30
Background Reference 03
Xue HH, et al. (2002) Int Immunol 14, 1263-71
Other Product Names
Signal transducer and activator of transcription 5B, STA5B, STAT5, transcription factor STAT5B
Tested Applications
WB
Protein ID
4504281
Physical Properties
Liquid
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