N-NOS (phospho Ser852) Antibody

Product Specifications

Background

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

NCBI Gene ID

4842

Swiss Prot

P29475

Accession Number

NP_000611.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

N-NOS (phospho Ser852) antibody was raised against a peptide sequence around phosphorylation site of serine 852 (F-N-S (p) -V-S) derived from Human n-NOS .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

120, 160 kDa

Fragment

IgG

Specificity

The antibody detects endogenous level of n-NOS only when phosphorylated at serine 852.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

NOS1

NCBI Official Name

Nitric oxide synthase 1 (neuronal)

NCBI Organism

Homo sapiens

Background Reference 01

Capettini LS, et al. (2011) DBr J Pharmacol 164, 1738-48

Background Reference 02

Ferreira JM, Burnett AL, Rameau GA (2011) J Neurosci 31, 1991-9

Background Reference 03

Chaudhury A, Rao YM, Goyal RK (2008) Am J Physiol Gastrointest Liver Physiol 295, G442-51

Other Product Names

BNOS, Constitutive NOS, IHPS1, N-NOS, NC-NOS

Tested Applications

Protein ID

10835173

Physical Properties

Liquid

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