Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Smad3 (phospho Thr179) Antibody

Product Specifications

Background

Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

NCBI Gene ID

4088

Swiss Prot

P84022

Accession Number

NP_001138574.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Smad3 (phospho Thr179) antibody was raised against a peptide sequence around phosphorylation site of threonine179 (P-E-T (p) -P-P) derived from Human Smad3 .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=80-005

Calculated Molecular Weight

50 kDa

Fragment

IgG

Specificity

The antibody detects endogenous level of Smad3 only when phosphorylated at threonine 179.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

SMAD3

NCBI Official Name

SMAD family member 3

NCBI Organism

Homo sapiens

Background Reference 01

Cohen-Solal KA, et al. (2011) Pigment Cell Melanoma Res 24, 512-24

Background Reference 02

Zelivianski S, Cooley A, Kall R, Jeruss JS (2010) Mol

Background Reference 03

Cancer Res 8, 1375-87

Background Reference 04

Matsuura I, et al. (2010) J Biol Chem 285, 1754-64

Other Product Names

JV15-2, MAD-3, MADH3, Smad 3, Mothers against decapentaplegic homolog 3

Tested Applications

WB

Protein ID

223029440

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Moesin Rabbit pAb (APR19092N)
APR19092N-01 50 µL

Moesin Rabbit pAb (APR19092N)

Ask
View Details
Moesin Rabbit pAb (APR19092N)
APR19092N-02 100 µL

Moesin Rabbit pAb (APR19092N)

Ask
View Details
Moesin Rabbit pAb (APR19092N)
APR19092N-03 200 µL

Moesin Rabbit pAb (APR19092N)

Ask
View Details
ALB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
11719061 1.0 µg DNA

ALB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

Ask
View Details
Alpha-L-iduronidase
AP78427-01 50 µg

Alpha-L-iduronidase

Ask
View Details
Alpha-L-iduronidase
AP78427-02 100 µg

Alpha-L-iduronidase

Ask
View Details