ETK (phospho Tyr566) Antibody

Product Specifications

Background

Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility.

NCBI Gene ID

660

Swiss Prot

P51813

Accession Number

NP_001712.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

ETK (phospho Tyr566) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine566 (D-Q-Y (p) -V-S) derived from Human ETK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

78 kDa

Fragment

IgG

Specificity

The antibody detects endogenous level of ETK only when phosphorylated at tyrosine 566.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

BMX

NCBI Official Name

BMX non-receptor tyrosine kinase

NCBI Organism

Homo sapiens

Background Reference 01

Zhang R, et al. (2003) J Biol Chem 278, 51267-76

Background Reference 02

Tsai YT, et al. (2000) Mol Cell Biol 20, 2043-54

Other Product Names

BMX, BMX NON-receptor tyrosine kinase, Bone marrow kinase BMX, Epithelial and endothelial tyrosine kinase, NTK38

Tested Applications

Protein ID

1705489

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SR405459 1 Kit

3830403N18Rik Mouse siRNA Oligo Duplex (Locus ID 70691)

Ask

View Details

GB113869-50 50 μL

Anti-PAICS/PAIS Rabbit pAb

Ask

View Details

RC215661L1V 200 µL

MDA5 (IFIH1) (NM_022168) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details

MBS8410832-01 0.02 mg

Human DZIP1L Protein Lysate

Ask

View Details

MBS8410832-02 5x 0.02 mg

Human DZIP1L Protein Lysate

Ask

View Details

128445 100 µg

IL22 (Interleukin-22, IL-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible Factor, IL-TIF, ILTIF, ZCYTO18, UNQ3099/PRO10096, MGC79382, MGC79384)

Ask

View Details