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CRMP-2 (phospho Ser522) Antibody

Product Specifications

Background

CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.

NCBI Gene ID

1808

Swiss Prot

Q16555

Accession Number

NP_001377.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

CRMP-2 (phospho Ser522) antibody was raised against a peptide sequence around phosphorylation site of Serine 522 (K-T-S (p) -P-A) derived from Human CRMP-2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

62 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of DPYSL2 only when phosphorylated at serine 522.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

DPYSL2

NCBI Official Name

Dihydropyrimidinase-like 2

NCBI Organism

Homo sapiens

Background Reference 01

Goshima Y., Nature 376:509-514 (1995) .

Background Reference 02

Hamajima N., Gene 180:157-163 (1996) .

Background Reference 03

Kitamura K., DNA Res. 6:291-297 (1999) .

Other Product Names

CRMP2, DPYL2, DRP2, ULIP-2

Tested Applications

WB

Protein ID

3122051

Physical Properties

Liquid

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