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FGFR4 (phospho Tyr642) Antibody

Product Specifications

Background

Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.

NCBI Gene ID

2264

Swiss Prot

P22455

Accession Number

NP_002002.3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

FGFR4 (phospho Tyr642) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 642 (I-D-Y (p) -Y-K) derived from Human FGFR4 .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

90 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of FGFR4 only when phosphorylated at tyrosine 642.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

FGFR4

NCBI Official Name

Fibroblast growth factor receptor 4

NCBI Organism

Homo sapiens

Background Reference 01

Partanen J.M., EMBO J. 10:1347-1354 (1991) [PubMed: 1709094].

Background Reference 02

Ron D., J. Biol. Chem. 268:5388-5394 (1993) [PubMed: 7680645].

Background Reference 03

Takaishi S., Biochem. Biophys. Res. Commun. 267:658-662 (2000) [PubMed: 10631118].

Other Product Names

FGFR-4, CD_antigen=CD334, Fibroblast growth factor receptor 4, EC=2.7.10.1

Tested Applications

WB

Protein ID

47524173

Physical Properties

Liquid

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