What is the catalog number for VAV3 (phospho Tyr173) Antibody?

The catalog number for VAV3 (phospho Tyr173) Antibody is 79-939.

What sizes are available for VAV3 (phospho Tyr173) Antibody?

VAV3 (phospho Tyr173) Antibody is available in the following size(s): 0.1 mg.

Is VAV3 (phospho Tyr173) Antibody in stock?

VAV3 (phospho Tyr173) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

VAV3 (phospho Tyr173) Antibody

Product Specifications

Background

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

NCBI Gene ID

10451

Swiss Prot

Q9UKW4

Accession Number

NP_006104.4

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

VAV3 (phospho Tyr173) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 173 (E-V-Y (p) -E-D) derived from Human VAV3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

100 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of VAV3 only when phosphorylated at tyrosine 173.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

VAV3

NCBI Official Name

Vav 3 guanine nucleotide exchange factor

NCBI Organism

Homo sapiens

Background Reference 01

Trenkle T., Nucleic Acids Res. 26:3883-3891 (1998) .

Background Reference 02

Movilla N., Mol. Cell. Biol. 19:7870-7885 (1999) .

Other Product Names

VAV3, FLJ40431, Guanine nucleotide exchange factor VAV3

Tested Applications

Protein ID

120432044

Physical Properties

Liquid

Frequently Asked Questions

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