HDAC7A (phospho Ser155) Antibody

Product Specifications

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

51564

Swiss Prot

Q8WUI4

Accession Number

NP_056216.2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

HDAC7A (phospho Ser155) antibody was raised against a peptide sequence around phosphorylation site of Serine 155 (T-V-S (p) -E-P) derived from Human HDAC7A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

103 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of HDAC7A only when phosphorylated at serine 155.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

HDAC7

NCBI Official Name

Histone deacetylase 7

NCBI Organism

Homo sapiens

Background Reference 01

Walsh M.J., Submitted (FEB-2000) .

Background Reference 02

Zelent A., Submitted (MAY-2003) .

Background Reference 03

Sugano S., Nat. Genet. 36:40-45 (2004)

Other Product Names

HD7a, HDA7, HDAC7A

Tested Applications

Protein ID

30913097

Physical Properties

Liquid

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