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HS1 (phospho Tyr397) Antibody

Product Specifications

Background

Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression.

NCBI Gene ID

3059

Swiss Prot

P14317

Accession Number

NP_005326.2

Host

Rabbit

Reactivity

Human

Immunogen

HS1 (phospho Tyr397) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 397 (G-D-Y (p) -E-E) derived from Human HS1 .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

54 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of HS1 only when phosphorylated at tyrosine 397.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

HCLS1

NCBI Official Name

Hematopoietic cell-specific Lyn substrate 1

NCBI Organism

Homo sapiens

Background Reference 01

Kitamura D., Nucleic Acids Res. 17:9367-9379 (1989) .

Background Reference 02

Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

Background Reference 03

Ota T., Nat. Genet. 36:40-45 (2004) .

Other Product Names

HCLS1, LCKBP1, Hematopoietic cell- specific LYN substrate 1

Tested Applications

WB

Protein ID

167234422

Physical Properties

Liquid

Curated Selection

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