Tip60 (phospho Ser90) Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

NCBI Gene ID

10524

Swiss Prot

Q92993

Accession Number

NP_006379.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Tip60 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of Serine 90 (P-G-S (p) -P-E) derived from Human Tip60.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

58 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90.

Symbol

KAT5

NCBI Official Name

K (lysine) acetyltransferase 5

NCBI Organism

Homo sapiens

Background Reference 01

Kamine J., Virology 216:357-366 (1996) .

Background Reference 02

Sheridan A.M., Mol. Cell. Biol. 21:4470-4481 (2001) .

Background Reference 03

Legube G., Gene 310:161-168 (2003) .

Other Product Names

HTATIP, TI60, Tat-interactive protein-60

Tested Applications

IHC

Protein ID

36287069

Physical Properties

Liquid

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