PLD2 (phospho Tyr169) Antibody

Product Specifications

Background

Phosphatidylcholine (PC) -specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.

NCBI Gene ID

5338

Swiss Prot

O14939

Accession Number

NP_002654.3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

PLD2 (phospho Tyr169) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 169 (E-N-Y (p) -L-N) derived from Human PLD2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

95 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of PLD2 only when phosphorylated at tyrosine 169.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

PLD2

NCBI Official Name

Phospholipase D2

NCBI Organism

Homo sapiens

Background Reference 01

Steed P.M., FASEB J. 12:1309-1317 (1998) .

Background Reference 02

Lopez I., J. Biol. Chem. 273:12846-12852 (1998) .

Background Reference 03

Divecha N., EMBO J. 19:5440-5449 (2000) .

Other Product Names

PLD 2, PLD1C, choline phosphatase 2

Tested Applications

WB, IHC

Protein ID

156564407

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ARG19444 1 Million

MEF2D Knockout K562 Polyclonal Cells

Ask

View Details

EIA07767Bo 1 Kit

Bovine keratinocyte differentiation-associated protein (KRTDAP) ELISA Kit

Ask

View Details

GTR15359786 1 Vial

Lentiviral human SRRM4 sgRNA gene knockout kit - Lentiviral human SRRM4 sgRNA gene knockout kit (plasmid)

Ask

View Details

037264-ML550 100 µL

Kallikrein 7, CT (KLK7, PRSS6, SCCE, Kallikrein-7, Serine protease 6, Stratum corneum chymotryptic enzyme) (MaxLight 550) discontinued

Ask

View Details

32752-05161 5x 30 µg

Human TNFSF18 AssayLite™ Antibody (APC Conjugate)

Ask

View Details