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MEF2C (phospho Ser396) Antibody

Product Specifications

Background

MEF2C transcription factor of the MADS family which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. May be involved in myogenesis, neurogenesis and in the development of cortical architecture. Three splice-variant isoforms have been described.

NCBI Gene ID

4208

Swiss Prot

Q06413

Accession Number

NP_001180279.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

MEF2C (phospho Ser396) antibody was raised against a peptide sequence around phosphorylation site of Serine 396 (P-V-S (p) -P-P) derived from Human MEF2C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-917

Calculated Molecular Weight

51 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of MEF2C only when phosphorylated at serine 396.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

MEF2C

NCBI Official Name

Myocyte enhancer factor 2C

NCBI Organism

Homo sapiens

Background Reference 01

Leifer D., Proc. Natl. Acad. Sci. U.S.A. 90:1546-1550 (1993) .

Background Reference 02

McDermott J.C., Mol. Cell. Biol. 13:2564-2577 (1993) .

Background Reference 03

Wang A.H., Mol. Cell. Biol. 19:7816-7827 (1999) .

Other Product Names

Myocyte enhancer factor 2C, Myocyte-specific enhancer factor 2C, Similar to MADS box transcription enhancer factor 2 polypeptide C

Tested Applications

WB, IHC

Protein ID

2500875

Physical Properties

Liquid

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