MDC1 (phospho Ser513) Antibody
Product Specifications
Background
The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.
NCBI Gene ID
9656
Swiss Prot
Q14676
Accession Number
NP_055456.2
Host
Rabbit
Reactivity
Human
Immunogen
MDC1 (phospho Ser513) antibody was raised against a peptide sequence around phosphorylation site of Serine 513 (E-R-S (p) -Q-A) derived from Human MDC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
226 kDa
Fragment
IgG
Specificity
The antibody detects endogenous levels of MDC1 only when phosphorylated at serine 513.
Symbol
MDC1
NCBI Official Name
Mediator of DNA-damage checkpoint 1
NCBI Organism
Homo sapiens
Background Reference 01
Nagase T., DNA Res. 3:17-24 (1996) .
Background Reference 02
Shiina T., Genetics 173:1555-1570 (2006) .
Background Reference 03
Mungall A.J., Nature 425:805-811 (2003) .
Other Product Names
IER3, NFBD1, KIAA0170, DKFZp781A0122
Tested Applications
IHC
Protein ID
132626688
Physical Properties
Liquid
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