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Estrogen Receptor-alpha (phospho Ser102) Antibody

Product Specifications

Background

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

NCBI Gene ID

2099

Swiss Prot

P03372

Accession Number

NP_000116.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Estrogen Receptor-alpha (phospho Ser102) antibody was raised against a peptide sequence around phosphorylation site of Serine102 (L-N-S (p) -V-S) derived from Human Estrogen Receptor-alpha.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

53 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of Estrogen Receptor-alpha only when phosphorylated at serine 102.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

ESR1

NCBI Official Name

Estrogen receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Greene G.L., Science 231:1150-1154 (1986) .

Background Reference 02

Green S., Nature 320:134-139 (1986) .

Background Reference 03

Pink J.J., Nucleic Acids Res. 24:962-969 (1996) .

Other Product Names

ER, ESR, ESR1, ESTR, NR3A1

Tested Applications

WB, IHC

Protein ID

62821794

Physical Properties

Liquid

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