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CRMP-2 (phospho Thr509) Antibody

Product Specifications

Background

CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.

NCBI Gene ID

1808

Swiss Prot

Q16555

Accession Number

NP_001377.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

CRMP-2 (phospho Thr509) antibody was raised against a peptide sequence around phosphorylation site of threonine 509 (S-V-T (p) -P-K) derived from Human CRMP-2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

50 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of CRMP-2 only when phosphorylated at threonine 509.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

DPYSL2

NCBI Official Name

Dihydropyrimidinase-like 2

NCBI Organism

Homo sapiens

Background Reference 01

Miki Y., Science 266:66-71 (1994) .

Background Reference 02

Smith T.M., Genome Res. 6:1029-1049 (1996) .

Background Reference 03

Wilson C.A., Oncogene 14:1-16 (1997) .

Other Product Names

CRMP2, N2A3, TOAD-64, DPYL2, ULIP2

Tested Applications

WB, IHC

Protein ID

3122051

Physical Properties

Liquid

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