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Claudin 7 (phospho Tyr210) Antibody

Product Specifications

Background

Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells.

NCBI Gene ID

1366

Swiss Prot

O95471

Accession Number

NP_001171951.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Claudin 7 (phospho Tyr210) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 210 (S-K-E-Y (p) -V) derived from Human Claudin 7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

32 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of Claudin 7 only when phosphorylated at tyrosine 210.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

CLDN7

NCBI Official Name

Claudin 7

NCBI Organism

Homo sapiens

Background Reference 01

Keen T.J.; Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.

Background Reference 02

Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

Background Reference 03

The MGC Project Team; Genome Res. 14:2121-2127 (2004) .

Other Product Names

CEPTRL2, claudin 7, CLD7, CPETRL2, CLDN7

Tested Applications

WB

Protein ID

311033475

Physical Properties

Liquid

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