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HP1alpha (phospho Ser92) Antibody

Product Specifications

Background

Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing.

NCBI Gene ID

23468

Swiss Prot

P45973

Accession Number

NP_001120793.1

Host

Rabbit

Reactivity

Human

Immunogen

HP1alpha (phospho Ser92) antibody was raised against a peptide sequence around phosphorylation site of Serine 92 (R-S-S (p) -N-F) derived from Human HP1alpha .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-887

Calculated Molecular Weight

22 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of HP1alpha only when phosphorylated at serine 92.

Symbol

CBX5

NCBI Official Name

Chromobox homolog 5

NCBI Organism

Homo sapiens

Background Reference 01

Saunders W.S., J. Cell Sci. 104:573-582 (1993) .

Background Reference 02

Ye Q., J. Biol. Chem. 271:14653-14656 (1996) .

Background Reference 03

Ye Q., J. Biol. Chem. 272:14983-14989 (1997) .

Other Product Names

HP1A, HP1 alpha, antigen p25

Tested Applications

IHC

Protein ID

6912292

Physical Properties

Liquid

Curated Selection

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