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HP1alpha (phospho Ser92) Antibody

Product Specifications

Background

Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing.

NCBI Gene ID

23468

Swiss Prot

P45973

Accession Number

NP_001120793.1

Host

Rabbit

Reactivity

Human

Immunogen

HP1alpha (phospho Ser92) antibody was raised against a peptide sequence around phosphorylation site of Serine 92 (R-S-S (p) -N-F) derived from Human HP1alpha .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

22 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of HP1alpha only when phosphorylated at serine 92.

Symbol

CBX5

NCBI Official Name

Chromobox homolog 5

NCBI Organism

Homo sapiens

Background Reference 01

Saunders W.S., J. Cell Sci. 104:573-582 (1993) .

Background Reference 02

Ye Q., J. Biol. Chem. 271:14653-14656 (1996) .

Background Reference 03

Ye Q., J. Biol. Chem. 272:14983-14989 (1997) .

Other Product Names

HP1A, HP1 alpha, antigen p25

Tested Applications

IHC

Protein ID

6912292

Physical Properties

Liquid

Curated Selection

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