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Paxillin (phospho Ser178) Antibody

Product Specifications

Background

Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) .

NCBI Gene ID

5829

Swiss Prot

P49023

Accession Number

NP_001074324.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Paxillin (phospho Ser178) antibody was raised against a peptide sequence around phosphorylation site of Serine 178 (A-L-S (p) -P-L) derived from Human Paxillin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

60 kDa

Fragment

IgG

Specificity

The Antibody detects endogenous levels of Paxillin only when phosphorylated at Ser178.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

PXN

NCBI Official Name

Paxillin

NCBI Organism

Homo sapiens

Background Reference 01

S Chen L.B., Griffin J.D. J. Biol. Chem. 270:5039-5047 (1995)

Background Reference 02

Bell G.I.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases

Other Product Names

Paxillin, PXN

Tested Applications

WB

Protein ID

170932514

Physical Properties

Liquid

Curated Selection

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