Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

TOP2A (phospho Thr1343) Antibody

Product Specifications

Background

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event.

NCBI Gene ID

7153

Swiss Prot

P11388

Accession Number

NP_001058.2

Host

Rabbit

Reactivity

Human

Immunogen

TOP2A (phospho Thr1343) antibody was raised against a peptide sequence around phosphorylation site of threonine1343 (E-K-T (p) -D-D) derived from Human TOP2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-874

Calculated Molecular Weight

190 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of TOP2A only when phosphorylated at threonine 1343.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

TOP2A

NCBI Official Name

Topoisomerase (DNA) II alpha 170kDa

NCBI Organism

Homo sapiens

Background Reference 01

Tsai-Pflugfelder M., Proc. Natl. Acad. Sci. U.S.A. 85:7177-7181 (1988) .

Background Reference 02

Wasserman R.A., Cancer Res. 53:3591-3596 (1993) .

Background Reference 03

Lang A.J., Gene 221:255-266 (1998) .

Other Product Names

TP2A, TOP2, TOP2A, P11388-1

Tested Applications

WB

Protein ID

19913406

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse GDNF shRNA Plasmid
abx970512-01 150 µg

Mouse GDNF shRNA Plasmid

Ask
View Details
Mouse GDNF shRNA Plasmid
abx970512-02 300 µg

Mouse GDNF shRNA Plasmid

Ask
View Details
Human Integrin Alpha-L (ITGAL) Protein
abx067847-01 10 µg

Human Integrin Alpha-L (ITGAL) Protein

Ask
View Details
Human Integrin Alpha-L (ITGAL) Protein
abx067847-02 50 µg

Human Integrin Alpha-L (ITGAL) Protein

Ask
View Details
Human Integrin Alpha-L (ITGAL) Protein
abx067847-03 100 µg

Human Integrin Alpha-L (ITGAL) Protein

Ask
View Details
Human Integrin Alpha-L (ITGAL) Protein
abx067847-04 200 µg

Human Integrin Alpha-L (ITGAL) Protein

Ask
View Details