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OSR1 (phospho Thr185) Antibody

Product Specifications

Background

Oxidative-stress responsive 1 gene is located in the vicinity of three others genes - GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stress

NCBI Gene ID

9943

Swiss Prot

O95747

Accession Number

NP_005100.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

OSR1 (phospho Thr185) antibody was raised against a peptide sequence around phosphorylation site of threonine185 (R-K-T (p) -F-V) derived from Human OSR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

65 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of OSR1 only when phosphorylated at threonine 185.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

OXSR1

NCBI Official Name

Oxidative stress responsive 1

NCBI Organism

Homo sapiens

Background Reference 01

Tamari M., J. Hum. Genet. 44:116-120 (1999) .

Background Reference 02

Kikuno R., DNA Res. 6-197-205 (1999) .

Background Reference 03

The MGC Project Team; Genome Res. 14:2121-2127 (2004) .

Other Product Names

OXSR1, kinase OSR1, Oxidative-stress responsive 1

Tested Applications

WB, IHC

Protein ID

4826878

Physical Properties

Liquid

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