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SHP-1 (phospho Tyr564) Antibody

Product Specifications

Background

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

NCBI Gene ID

5777

Swiss Prot

P29350

Accession Number

NP_002822.2

Host

Rabbit

Reactivity

Human

Immunogen

SHP-1 (phospho Tyr564) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 564 (D-V-Y (p) -E-N) derived from Human SHP-1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

70 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of SHP-1 only when phosphorylated at tyrosine 564.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

PTPN6

NCBI Official Name

Protein tyrosine phosphatase, non-receptor type 6

NCBI Organism

Homo sapiens

Background Reference 01

Yi T., Mol. Cell. Biol. 12:836-846 (1992) .

Background Reference 02

Shen S.H., Nature 352:736-739 (1991) .

Background Reference 03

Plutzky J., Proc. Natl. Acad. Sci. U.S.A. 89:1123-1127 (1992) .

Other Product Names

HCP, HCPH, PTN6, PTP1C, SHP1

Tested Applications

WB

Protein ID

18104989

Physical Properties

Liquid

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