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PDK1 (phospho Tyr9) Antibody

Product Specifications

Background

Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development.

NCBI Gene ID

5170

Swiss Prot

O15530

Accession Number

NP_002604.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

PDK1 (phospho Tyr9) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 9 (A-L-Y (p) -D-A) derived from Human PDK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

63 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of PDK1 only when phosphorylated at tyrosine 9.

Symbol

PDPK1

NCBI Official Name

3-phosphoinositide dependent protein kinase-1

NCBI Organism

Homo sapiens

Background Reference 01

Alessi D.R., Curr. Biol. 7:261-269 (1997) .

Background Reference 02

Alessi D.R., Curr. Biol. 7:776-789 (1997) .

Background Reference 03

Stephens L.R., Science 279:710-714 (1998)

Other Product Names

HPDK1, PDPK1, mPDK1, PkB kinase

Tested Applications

IHC

Protein ID

4505695

Physical Properties

Liquid

Curated Selection

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