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C-Jun (phospho Ser63) Antibody

Product Specifications

Background

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.

NCBI Gene ID

3725

Swiss Prot

P05412

Accession Number

NP_002219.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

C-Jun (phospho Ser63) antibody was raised against a peptide sequence around phosphorylation site of Serine 63 (L-T-S (p) -P-D) derived from Human c-Jun.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

48 kDa

Fragment

IgG

Specificity

The Antibody detects endogenous levels of c-Jun only when phosphorylated at Serine 63.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

JUN

NCBI Official Name

Jun proto-oncogene

NCBI Organism

Homo sapiens

Background Reference 01

Wei W, et al. (2005) . Cancer Cell. 8 (1) : 25-33.

Background Reference 02

Sevilla A, et al. (2004) . Oncogene.23 (55) : 8950-8958.

Background Reference 03

Li L, et al. (2004) . J Biol Chem.279 (6) : 4058-4065.

Background Reference 04

Hurd C, et al. (2002) . Oncogene.21 (14) : 2154-2160.

Other Product Names

AH119, c-Jun, p39, Jun A, AP1

Tested Applications

WB, IHC

Protein ID

4758616

Physical Properties

Liquid

Curated Selection

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