Nuclear Receptor NR4A1 (phospho Ser351) Antibody

Product Specifications

Background

Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.

NCBI Gene ID

3164

Swiss Prot

P22736

Accession Number

NP_002126.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Nuclear Receptor NR4A1 (phospho Ser351) antibody was raised against a peptide sequence around phosphorylation site of Serine351 (L-P-S (p) -K-P) derived from Human Nuclear Receptor NR4A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

64 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of Nuclear Receptor NR4A1 only when phosphorylated at serine 351

Symbol

NR4A1

NCBI Official Name

Nuclear receptor subfamily 4, group A, member 1

NCBI Organism

Homo sapiens

Background Reference 01

Nakai A., Mol. Endocrinol. 4:1438-1443 (1990) .

Background Reference 02

Chang C., J. Steroid Biochem. 34:391-395 (1989) .

Background Reference 03

Bondy G.P., Cell Growth Differ. 2:203-208 (1991)

Other Product Names

NGFIB, GFRP1, HMR, NR4A1, NAK1

Tested Applications

IHC

Protein ID

27894346

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

sc-65762 200 µg/mL

AChRδ (166)

Ask

View Details

ABP59812-01 30 µL

PACS1 Polyclonal Antibody

Ask

View Details

ABP59812-02 100 µL

PACS1 Polyclonal Antibody

Ask

View Details

ABP59812-03 200 µL

PACS1 Polyclonal Antibody

Ask

View Details

NBP2-48011AF700 0.1 mL

Mouse Monoclonal ER alpha/NR3A1 Antibody (ESR1/420) [Alexa Fluor 700]

Ask

View Details

BS40521-01 50 µL

CRISPR-Cas9 SA Rabbit monoclonal antibody

Ask

View Details