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ITGB4 (phospho Tyr1510) Antibody

Product Specifications

Background

Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.

NCBI Gene ID

3691

Swiss Prot

P16144

Accession Number

NP_000204.3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

ITGB4 (phospho Tyr1510) antibody was raised against a peptide sequence around phosphorylation site of tyrosine1510 (R-D-Y (p) -S-T) derived from Human ITGB4 .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

202 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of ITGB4 only when phosphorylated at tyrosine 1510.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

ITGB4

NCBI Official Name

Integrin, beta 4

NCBI Organism

Homo sapiens

Background Reference 01

Suzuki S., EMBO J. 9:757-763 (1990) .

Background Reference 02

Hogervorst F., EMBO J. 9:765-770 (1990) .

Background Reference 03

Tamura R.N., J. Cell Biol. 111:1593-1604 (1990) .

Other Product Names

GP150, ITB4, CD104 antigen

Tested Applications

WB, IHC

Protein ID

317373584

Physical Properties

Liquid

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