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IL-2R beta/CD122 (phospho Tyr364) Antibody

Product Specifications

Background

Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

NCBI Gene ID

3560

Swiss Prot

P14784

Accession Number

NP_000869.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

IL-2R beta/CD122 (phospho Tyr364) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 364 (Q-G-Y (p) -F-F) derived from Human IL-2Rbeta/CD122 .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

75 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of IL-2Rbeta/CD122 only when phosphorylated at tyrosine 364.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

IL2RB

NCBI Official Name

Interleukin 2 receptor, beta

NCBI Organism

Homo sapiens

Background Reference 01

Hatakeyama M., Science 244:551-556 (1989) .

Background Reference 02

Dunham I., Nature 402:489-495 (1999) .

Background Reference 03

Mulloy J.C., J. Virol. 70:3599-3605 (1996)

Other Product Names

CD122 antigen, P70-75, IL-2 receptor, IL-2R beta

Tested Applications

WB

Protein ID

124321

Physical Properties

Liquid

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