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Histamine H1 Receptor (phospho Ser398) Antibody

Product Specifications

Background

In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.

NCBI Gene ID

3269

Swiss Prot

P35367

Accession Number

NP_000852.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Histamine H1 Receptor (phospho Ser398) antibody was raised against a peptide sequence around phosphorylation site of Serine 398 (S-H-S (p) -R-Q) derived from Human Histamine H1 Receptor .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

55 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of Histamine H1 Receptor only when phosphorylated at serine 398.

Symbol

HRH1

NCBI Official Name

Histamine receptor H1

NCBI Organism

Homo sapiens

Background Reference 01

De Backer M.D., Biochem. Biophys. Res. Commun. 197:1601-1608 (1993) .

Background Reference 02

Fukui K., Biochem. Biophys. Res. Commun. 201:894-901 (1994) .

Background Reference 03

Sjoeblom T., Science 314:268-274 (2006)

Other Product Names

H1-R, HRH1, histamine H1 receptor

Tested Applications

IF

Protein ID

4504491

Physical Properties

Liquid

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