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PKA-R2beta (phospho Ser113) Antibody

Product Specifications

Background

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

NCBI Gene ID

5577

Swiss Prot

P31323

Accession Number

NP_002727.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

PKA-R2beta (phospho Ser113) antibody was raised against a peptide sequence around phosphorylation site of Serine113 (R-R-A (p) -S-V) derived from Human PKA-R2beta.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

46 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of PKA-R2beta only when phosphorylated at serine 113.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

PRKAR2B

NCBI Official Name

Protein kinase, cAMP-dependent, regulatory, type II, beta

NCBI Organism

Homo sapiens

Background Reference 01

Levy F.O., Mol. Endocrinol. 2:1364-1373 (1988) .

Background Reference 02

DeGiorgis J.A., J. Proteome Res. 4:306-315 (2005) .

Background Reference 03

Han G., Proteomics 8:1346-1361 (2008)

Other Product Names

KAP3, PRKAR2B, PKA R2-beta

Tested Applications

WB

Protein ID

47132585

Physical Properties

Liquid

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