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JAK2 (phospho Tyr570) Antibody

Product Specifications

Background

Plays a role in leptin signaling and control of body weight.

NCBI Gene ID

3717

Swiss Prot

O60674

Accession Number

NP_004963.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

JAK2 (phospho Tyr570) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 570 (G-D-Y (p) -G-Q) derived from Human JAK2 .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

125 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 750.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

JAK2

NCBI Official Name

Janus kinase 2

NCBI Organism

Homo sapiens

Background Reference 01

Saltzman A., Biochem. Biophys. Res. Commun. 246:627-633 (1998) .

Background Reference 02

Dalal I., Blood 91:844-851 (1998) .

Background Reference 03

Peeters P., Blood 90:2535-2540 (1997) .

Other Product Names

JAK2, Janus kinase 2, kinase Jak2

Tested Applications

WB

Protein ID

4826776

Physical Properties

Liquid

Frequently Asked Questions

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