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CD3 zeta (phospho Tyr142) Antibody

Product Specifications

Background

Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.

NCBI Gene ID

919

Swiss Prot

P20963

Accession Number

NP_000725.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

CD3 zeta (phospho Tyr142) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 142 (G-L-Y (p) -Q-G) derived from Human CD3 ζ.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

20 kDa

Fragment

IgG

Specificity

The antibody detects endogenous levels of CD3 ζ only when phosphorylated at tyrosine 142.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

CD247

NCBI Official Name

CD247 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Linda A. Trimble, Blood, Aug 2000; 96: 1021 - 1029.

Background Reference 02

Sandeep Krishnan, J. Immunol., Sep 2005; 175: 3417 - 3423.

Background Reference 03

Linda A. Trimble, J. Virol., Aug 2000; 74: 7320 - 7330.

Background Reference 04

Hisashi Arase, J. Immunol., Jan 2001; 166: 21.

Other Product Names

T3Z, CD3-zeta, TCRZ, T-cell receptor T3 zeta chain

Tested Applications

WB

Protein ID

23830999

Physical Properties

Liquid

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