IGFBP 3 Antibody

Product Specifications

Background

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

NCBI Gene ID

3486

Swiss Prot

P17936

Accession Number

NP_001013416.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

IGFBP-3 antibody was raised against a peptide sequence around aa.185~189 (R-Y-K-V-D) derived from Human IGFBP-3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

24 - 41 kDa

Specificity

This antibody detects endogenous level of total IGFBP-3 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

IGFBP3

NCBI Official Name

Insulin-like growth factor binding protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Roghani M., Segovia B., Whitechurch O., Binoux M. Growth Regul. 1:125-130 (1991) Ikonen M., Liu B., Hashimoto Y., Ma L., Lee K. W., Niikura T., Nishimoto I., Cohen P. Proc. Natl. Acad. Sci. U. S. A. 100:13042-13047 (2003) Zhou W., Ross M. M., Tessitore A., Ornstein D., Vanmeter A., Liotta L. A., Petricoin E. F. IIIJ. Proteome Res. 8:5523-5531 (2009)