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DP1 Antibody

Product Specifications

Background

Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.

NCBI Gene ID

7027

Swiss Prot

Q14186

Accession Number

NP_009042.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

DP-1 antibody was raised against a peptide sequence around aa.13~17 (E-L-K-V-F) derived from Human DP-1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

45 kDa

Specificity

This antibody detects endogenous levels of total DP-1 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

TFDP1

NCBI Official Name

Transcription factor Dp-1

NCBI Organism

Homo sapiens

Background Reference 01

Wu C. -L., Zukerberg L. R., Ngwu C., Harlow E., Lees J. A. Mol. Cell. Biol. 15:2536-2546 (1995)

Other Product Names

DP1, Dp-1, DRTF1, ERK1, PRKM3, TFDP1

Tested Applications

WB

Protein ID

6005900

Physical Properties

Liquid

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