Dynamin 1 Antibody

Product Specifications

Background

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis

NCBI Gene ID

1759

Swiss Prot

Q05193

Accession Number

NP_001005336.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Dynamin 1 antibody was raised against a peptide sequence around aa.774~778 (S-P-T-S-S) derived from Human Dynamin 1 .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

100 kDa

Specificity

This antibody detects endogenous levels of total Dynamin 1 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

DNM1

NCBI Official Name

Dynamin 1

NCBI Organism

Homo sapiens

Background Reference 01

"SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis. "Soulet F., Yarar D., Leonard M., Schmid S. L. Mol. Biol. Cell 16:2058-2067 (2005)