Synaptophysin Antibody

Product Specifications

Background

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity

NCBI Gene ID

6855

Swiss Prot

P08247

Accession Number

NP_003170.1

Host

Rabbit

Reactivity

Human

Immunogen

Synaptophysin antibody was raised against a peptide sequence around aa.305~309 (A-P-T-S-F) derived from Human Synaptophysin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

38 kDa

Specificity

This antibody detects endogenous levels of total Synaptophysin protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

SYP

NCBI Official Name

Synaptophysin

NCBI Organism

Homo sapiens

Background Reference 01

"Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex. "Ito H., Atsuzawa K., Sudo K., Di Stefano P., Iwamoto I., Morishita R., Takei S., Semba R., Defilippi P., Asano T., Usuda N., Nagata K. J. Neurochem. 107:61-72 (2008) "A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. "Tarpey P. S., Smith R., Pleasance E., et al. Nat. Genet. 41:535-543 (2009)