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Gamma Catenin Antibody

Product Specifications

Background

Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton

NCBI Gene ID

3728

Swiss Prot

P14923

Accession Number

NP_002221.1

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Gamma-Catenin antibody was raised in was raised against a peptide sequence around aa.726~730 (I-D-T-Y-S) derived from Human gamma-Catenin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-746

Calculated Molecular Weight

83 kDa

Specificity

This antibody detects endogenous levels of total gamma-Catenin protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

JUP

NCBI Official Name

Junction plakoglobin

NCBI Organism

Homo sapiens

Other Product Names

DP3, PDGB, PKGB, CTNNG, DPIII, ARVD12, DP3

Tested Applications

WB

Protein ID

4504811

Physical Properties

Liquid

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