A Internexin Antibody

Product Specifications

Background

Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.

NCBI Gene ID

9118

Swiss Prot

Q16352

Accession Number

NP_116116.1

Host

Rabbit

Reactivity

Human

Immunogen

A-Internexin antibody was raised against a peptide sequence around aa.491~495 (E-T-T-I-S) derived from Human α -Internexin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

66 kDa

Specificity

This antibody detects endogenous level of total α -Internexin protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

INA

NCBI Official Name

Internexin neuronal intermediate filament protein, alpha

NCBI Organism

Homo sapiens

Background Reference 01

Matsuoka S., Ballif B. A., Smogorzewska A., McDonald E. R. III, Hurov K. E., Luo J., Bakalarski C. E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S. P., Elledge S. J. Science 316:1160-1166 (2007)