VEGFR1 Antibody

Product Specifications

Background

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

NCBI Gene ID

2321

Swiss Prot

P17948

Accession Number

NP_002010.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

VEGFR1 antibody was raised against a peptide sequence around aa.31~35 (D-P-E-L-S) derived from Human VEGFR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

180 kDa

Specificity

This antibody detects endogenous level of total VEGFR1 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

FLT1

NCBI Official Name

Fms-related tyrosine kinase 1

NCBI Organism

Homo sapiens

Background Reference 01

Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J., Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L., Mitchell J., Wetzel R., Macneill J., Ren J. M. Comb M. J. Cell 131:1190-1203 (2007)